LEPR Genetics: Leptin Resistance, Weight Management, Metabolism
Your LEPR variant shapes leptin sensitivity and how hard weight loss feels — check your own LEPR from your 23andMe or AncestryDNA raw data.
23-Apr 2026•32 min read
Genomic wellness library
Expert articles on genetics, nutrition, and wellness — backed by science, personalized by your DNA.
Showing 21 of 247 articles
LEP Genetics: Leptin Production, Appetite Control, Obesity Risk
Your LEP variant sets your baseline leptin and how full you feel after eating — check your own LEP from your 23andMe or AncestryDNA raw data.
22-Apr 2026•38 min read
IRS1 Genetics: Insulin Signaling, Metabolic Syndrome, Diabetes Risk
IRS1 insulin signaling genetics refers to variations in the insulin receptor substrate 1 gene affecting cellular insulin response and glucose metabolism. You...
21-Apr 2026•49 min read
PPARG Genetics: Insulin Sensitivity, Fat Storage, Diabetes, Drug Response
PPARG insulin sensitivity genetics determines how your body responds to insulin, stores fat, and processes glucose. The PPARG gene encodes peroxisome prolife...
20-Apr 2026•43 min read
SLC30A8 Genetics: Zinc Transport, Insulin Secretion, Diabetes
Your SLC30A8 variant affects insulin release and type 2 diabetes risk — check your own SLC30A8 from your 23andMe or AncestryDNA raw data.
19-Apr 2026•25 min read
KCNJ11 Genetics: Type 2 Diabetes, Insulin Secretion, Sulfonylurea Response
The KCNJ11 gene encodes the Kir6.2 protein, forming pancreatic ATP-sensitive potassium channels that control insulin secretion. Variants directly affect how ...
18-Apr 2026•29 min read
ANGPTL3 Genetics: Triglycerides, Cholesterol, Metabolic Health
The ANGPTL3 gene regulates lipid metabolism by controlling triglyceride and cholesterol levels through inhibition of lipoprotein lipase and endothelial lipas...
17-Apr 2026•45 min read
LPA Genetics: Lipoprotein(a), Heart Attack, Stroke Risk
Your LPA gene sets Lp(a) that raises heart attack and stroke risk—diet won't lower it. Check your LPA in your 23andMe or AncestryDNA raw data.
16-Apr 2026•41 min read
APOA5 Genetics: Triglycerides, Heart Disease, Pancreatitis
APOA5 triglyceride genetics refers to variations in the APOA5 gene that significantly influence how your body processes fats in the bloodstream. This gene en...
15-Apr 2026•27 min read
CETP Genetics: HDL Cholesterol, Heart Disease Protection
CETP hdl genetics refers to how variants in the CETP gene influence HDL cholesterol levels and cardiovascular disease risk. CETP encodes cholesteryl ester tr...
14-Apr 2026•43 min read
LIPC Genetics: HDL Cholesterol, Triglyceride Metabolism
The LIPC gene encodes hepatic lipase, a critical enzyme regulating HDL cholesterol and triglyceride levels in your blood. Genetic variants in LIPC directly i...
13-Apr 2026•32 min read
APOB Genetics: LDL Cholesterol, Cardiovascular Disease Risk
Your APOB gene determines how your body produces apolipoprotein B, the primary protein component of LDL cholesterol particles. Variations in APOB directly in...
12-Apr 2026•17 min read
LDLR Genetics: Familial Hypercholesterolemia, Early Heart Disease
LDLR mutations cause familial high cholesterol from birth and early heart disease. Check your own LDLR in your 23andMe or AncestryDNA raw data.
11-Apr 2026•50 min read
PCSK9 Genetics: LDL Cholesterol, Heart Disease, Drug Response
PCSK9 variants can lower your LDL up to 40% or sharply raise heart risk. Check your own PCSK9 in your 23andMe or AncestryDNA raw data.
10-Apr 2026•44 min read
MBOAT7 Genetics: Liver Fibrosis, NAFLD Progression, Cirrhosis
Complete guide to mboat7 liver disease genetics. Learn about genetic mechanisms, health impact, testing options, and personalized strategies.
9-Apr 2026•32 min read
TM6SF2 Genetics: Liver Fat, Cardiovascular Risk, Metabolic Syndrome
Complete guide to tm6sf2 liver fat cardiovascular genetics. Learn about genetic mechanisms, health impact, testing options, and personalized strategies.
8-Apr 2026•20 min read
PNPLA3 Genetics: Fatty Liver Disease, NAFLD, Cirrhosis Risk
Complete guide to pnpla3 nafld fatty liver genetics. Learn about genetic mechanisms, health impact, testing options, and personalized strategies.
7-Apr 2026•36 min read
FAAH Genetics: Endocannabinoid Breakdown, Anxiety, Pain Threshold
FAAH sets how fast you clear anandamide, your “bliss molecule.” See what your rs324420 variant means for anxiety and pain — check your own DNA raw data.
6-Apr 2026•27 min read
CNR1 Genetics: Endocannabinoid System, Appetite, Mood, Pain
Complete guide to cnr1 endocannabinoid system genetics. Learn about genetic mechanisms, health impact, testing options, and personalized strategies.
5-Apr 2026•27 min read
OPRM1 Genetics: Opioid Response, Pain Sensitivity, Addiction Risk
Complete guide to oprm1 opioid receptor pain addiction. Learn about genetic mechanisms, health impact, testing options, and personalized strategies.
4-Apr 2026•28 min read
CHRNA5 Genetics: Nicotine Dependence, Smoking Cessation, Lung Cancer
Complete guide to chrna5 nicotine dependence smoking. Learn about genetic mechanisms, health impact, testing options, and personalized strategies.
3-Apr 2026•24 min read