Paste your raw DNA file and get a decision for your variants — not population averages. Which form fits you, what to be careful with, and an overmethylation safety flag. Your first question is free.
We read your real genotypes from your file and answer the question you have right now
Free — no card
One-time pack, no subscription
Every time you buy your next supplement
Every answer is built from your own file in three steps.
Type a real question — "Is methylfolate right for my MTHFR, or will it overmethylate me?" We pick the exact markers it depends on (rs1801133, rs4680, MTRR…).
We extract your actual genotypes from your uploaded raw data — the real variants out of 600,000+ SNPs, not a fixed panel.
An answer for your specific variants — which form and starting point, with a safe / caution / avoid overmethylation flag. Plain ChatGPT can't load your file; static reports can't do this.
If your COMT is slow, methyl donors can tip you into overmethylation — anxiety, insomnia, irritability. We read that against your own file and flag safe / caution / avoid before you dose, so your next bottle doesn't set you back.
Educational, not medical advice. We don't prescribe doses — we help you ask sharper questions of your own genetics and your doctor.
The same personal read, whatever supplement decision you're facing today
"Is methylfolate right for my MTHFR + COMT — or will it overmethylate me?"
"Am I a slow CYP1A2 metabolizer — how much coffee, and how late?"
"Slow COMT and MAOA — which supplements help, which push me over?"
"GSTM1 null — should I take NAC, glutathione, or sulforaphane?"
"VDR variant — why does D never work for me, what dose and form?"
"DAO or HNMT — why do I react, and what actually helps?"
If you have a raw DNA file and a supplement decision, this is for you
"I need to know if methyl-B's fit my COMT before I dose them"
"I've crashed on methylfolate — I need an overmethylation check first"
"I want to stop guessing which supplements actually fit my genotype"
"I read r/MTHFR and I want answers from my own file, not averages"
I spent 2 years wondering why vitamin D never worked for me. It flagged a VDR variant that needs D3 with K2 and magnesium. My levels finally normalized.
Sarah M.
Biohacker, California
I kept crashing on methylfolate — anxiety, no sleep. It read my slow COMT and pointed me to a lower dose and a non-methyl form. The anxiety stopped.
Marcus T.
Self-experimenter, Austin
Asked why coffee gives me anxiety when my husband drinks 4 cups fine. I'm a slow CYP1A2 metabolizer — switched to one cup before noon and my sleep came back.
Elena K.
Software engineer, New York
by biohackers reading their own raw DNA files
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Peer-reviewed genetics databases, encrypted, never sold — delete anytime
Upload your raw data from any testing service and ask your first question free — a personal answer in under 60 seconds. Private and encrypted.
🔒 Works with 23andMe, Ancestry & 100+ more • Delete your data anytime • First question free — no card
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